Cochannel interference and multipath propagation reduce the performance of mobile communication systems. Multi-input MLSE with whitening processing can mitigate the influence of the interference and provide path diversity gain. In conventional considerations, however, the required complexity rapidly rises with the number of array elements. In this paper, we propose multi-input MLSE that whitens error signals in the signal space by using a multibeam adaptive array. This scheme can reduce the computational load of multi-input MLSE than the conventional type when using a large-element array. The results of an analysis show that the proposed type is equivalent to conventional one in the sense of the metric and provides less computational complexity.