This paper proposes an iterative parallel genetic algorithm with biased initial population to solve large-scale combinatorial optimization problems. The proposed scheme employs a master-slave collaboration in which the master node manages searched space of slave nodes and assigns seeds to generate initial population to slaves for their restarting of evolution process. Our approach allows us as widely as possible to search by all the slave nodes in the beginning period of the searching and then focused searching by multiple slaves on a certain spaces that seems to include good quality solutions. Computer experiment shows the effectiveness of our proposed scheme.