We propose an implementation of the tapped delay line adaptive array (TDLAA) at the base station for improving the BER performance of asynchronous multi-user mobile communication over fast fading channels using multiple antennas. The data of each user at the mobile station, which applies two transmit antennas, are encoded by Space Time Block Code (STBC). The proposed scheme transmits the pilot signal and information data in alternate time slots. We derive performance criteria for designing such a scheme under the assumption that the fading is classified as fast fading. We show that the proposed scheme can suppress co-channel interference (CCI) and defeat Doppler spread effectively.