This paper proposes a simulation framework suitable for holonic manufacturing systems, or HMS, based on the concept of distributed self-simulation. HMS is a distributed system that comprises autonomous and cooperative elements called holons, for the flexible and agile manufacturing. The simulation framework proposed here capitalizes on this distributed nature, where each holon functions similar to an independent simulator with self-simulation capabilities to maintain its own clock, handle events, and detect inter-holon state inconsistencies and perform rollback actions. This paper discusses the detailed architecture and design issues of such a simulator and reports on the results of a prototype.