Intelligent robot control systems based on multiprocessors, sensors, and actuators require a flexible network for communicating various types of real-time data (e.g. sensing data, interrupt signals). Furthermore, serial data transfer implemented using a few wiring lines is also required. Therefore, a CDMA serial communication interface with a new two-step synchronization technique is proposed to counter these problems. The transmitter and receiver fabricated by 0.25 µm digital CMOS technology achieve 2.7 Gcps (gigachips per second) and can multiplex 7 communication channels.