Multi-focus image fusion involves combining partially focused images of the same scene to create an all-in-focus image. Aiming at the problems of existing multi-focus image fusion algorithms that the benchmark image is difficult to obtain and the convolutional neural network focuses too much on the local region, a fusion algorithm that combines local and global feature encoding is proposed. Initially, we devise two self-supervised image reconstruction tasks and train an encoder-decoder network through multi-task learning. Subsequently, within the encoder, we merge the dense connection module with the PS-ViT module, enabling the network to utilize local and global information during feature extraction. Finally, to enhance the overall efficiency of the model, distinct loss functions are applied to each task. To preserve the more robust features from the original images, spatial frequency is employed during the fusion stage to obtain the feature map of the fused image. Experimental results demonstrate that, in comparison to twelve other prominent algorithms, our method exhibits good fusion performance in objective evaluation. Ten of the selected twelve evaluation metrics show an improvement of more than 0.28%. Additionally, it presents superior visual effects subjectively.