Transcatheter renal denervation (RDN) is a novel treatment to reduce blood pressure in patients with resistant hypertension using an energy-based catheter, mostly radio frequency (RF) current, by eliminating renal sympathetic nerve. However, several inconsistent RDN treatments were reported, mainly due to RF current narrow heating area, and the inability to confirm a successful nerve ablation in a deep area. We proposed microwave energy as an alternative for creating a wider ablation area. However, confirming a successful ablation is still a problem. In this paper, we designed a prediction method for deep renal nerve ablation sites using hybrid numerical calculation-driven machine learning (ML) in combination with a microwave catheter. This work is a first-step investigation to check the hybrid ML prediction capability in a real-world situation. A catheter with a single-slot coaxial antenna at 2.45 GHz with a balloon catheter, combined with a thin thermometer probe on the balloon surface, is proposed. Lumen temperature measured by the probe is used as an ML input to predict the temperature rise at the ablation site. Heating experiments using 6 and 8 mm hole phantom with a 41.3 W excited power, and 8 mm with 36.4 W excited power, were done eight times each to check the feasibility and accuracy of the ML algorithm. In addition, the temperature on the ablation site is measured for reference. Prediction by ML algorithm agrees well with the reference, with a maximum difference of 6°C and 3°C in 6 and 8 mm (both power), respectively. Overall, the proposed ML algorithm is capable of predicting the ablation site temperature rise with high accuracy.

In this paper, a method of separating the effects of the thermal diffusivity, durations and integral powers of the bridge and arc on the temperature rise of AgPd contacts was proposed. First, the effects of the Pd content on the durations and integral powers of the bridge and arc, and the temperature rise of the contacts were discussed. Because the integral power of bridge was larger than that of the arc under our experimental conditions of 40 V open-circuit, 5 A close-circuit and 100 µm/s opening velocity, the temperature rise of the contacts was dominated by the bridge. No remarked difference in bridge duration can be seen among the six materials. Although the integral power of the bridge in the case of Pd was maximum, the maximum temperature rise of the contact was observed in the case of AgPd60. To clarify the contribution of each factor, the effect of thermal diffusivity on the temperature rise of the contact was evaluated by the finite-difference time-domain (FDTD) method. In the case of Pd, because its thermal diffusivity was largest, heat diffused rapidly. On the other hand, the thermal diffusivity in the case of AgPd60 was small, and heat diffused slowly to the holders. The maximum temperature rise was observed in the case of AgPd60. It was demonstrated that the proposed method of separating the effects of thermal diffusivity, durations and integral powers of the bridge and arc on the temperature rise of contacts is effective in enabling us to understand contact phenomena.

In this paper, the separation of heat generation and heat transfer related to temperature rise of silver palladium contact was investigated experimentally in order to predict the temperature rise of contact by the use conditions such as voltage range between 25 to 40 V, current range between 3.2 to 5.0 A and silver palladium alloy (AgPd) materials. Firstly, relationship between temperature rise of contact and supply power was discussed. The effects of heat generation and heat transfer on temperature rise were separated and quantified by least squares method. Secondly, effects of durations and integral powers of bridge and arc on temperature rise were also discussed by changing supply power. Results show that the integral power of the bridge increases when supply power increases. As the supply power increases, integral power of arc also increases. The temperature rise is dominated by integral power of bridge. Remarkable difference of bridge duration can not be seen in the five materials (AgPd30, AgPd40, AgPd50, AgPd70 and Pd). The supply power is increased, arc duration gets longer. As weight percent of Pd content increases, the effect of supply power on arc duration becomes larger. Consequently, the integral power of arc increases. This study is a basic consideration to realize methods predicting temperature rise of contact.

The interaction between the human eye and electromagnetic (EM) waves in the ISM (industrial, scientific, and medical) frequency bands is investigated with the use of the finite-difference time-domain (FDTD) method. In order to assess possible health hazards, the specific absorption rates (SARs) are calculated and compared with the recommended safety standards. In particular, we calculate temperature rises in the human eye to assess the possibility of microwave-induced cataract formation. The results show that the maximum values of averaged SARs are less than the standard levels. In addition, we observed what is called the 'hot spot' in the region of eye humor at 2.4 GHz but not at 900 MHz and 5.8 GHz. Furthermore, the maximum temperature rise due to the incident EM power density of 5.0 mW/cm2, which is the MPE (maximum permissible exposure) limit for controlled environments, has been found to be at most 0.26 at 5.8 GHz, which is small compared with the threshold temperature rise 3.0 for cataract formation.